Astronauta de la NASA flotando en gravedad cero dentro de una nave espacial, visto en un plano amplio que muestra el interior lleno de paneles y equipos, con la Tierra visible a través de una ventana circular al fondo.

What happens to the human body in zero gravity

Mike Munay

We are used to seeing astronauts floating in space movies where everything seems easy and fun, but the reality is more difficult and our bodies face an enormous challenge to adapt to life without gravity.


From the moment a spacecraft leaves the atmosphere, the body starts doing very strange things: fluids move to the head, muscles begin to weaken, and even drinking a glass of water becomes an adventure. And that's just the beginning.

Do you really know what happens to your body when it stops feeling gravity?

In this article, I'll tell you how the human body reacts to weightlessness, what happens with everyday tasks up there, and how astronauts manage to adapt to an environment that is nothing like anything we know down here.

Get a coffee ready, because today you're going to learn some things about space.

What is zero gravity and at what distance from Earth does it begin?

The first thing to clarify is that zero gravity as such does not exist. What astronauts experience is called microgravity, a situation in which gravity is still acting but its effects are practically not felt. However, the reason why it occurs is not always the same. It depends on where the spacecraft is and what it is doing.

Case 1: orbiting the Earth

When a spacecraft orbits Earth, as the International Space Station does at an altitude of about 408 km, Earth's gravity is still approximately 90% of what we feel on the surface. What happens is that, as we explained in the article on how satellites work, the centrifugal force generated by orbital motion exactly equals the gravitational force pulling the spacecraft towards Earth, so the resultant force is zero and the spacecraft does not fall. The spacecraft and everything inside it are in this perfect balance, traveling at about 27,600 km/h. Since everything is subject to the same forces equally, no one feels the gravitational pull and everything appears to float. It is not an absence of gravity, it is a balance of forces that produces the same effect.

Case 2: traveling outside Earth's orbit towards another planet

When a spacecraft leaves orbit and travels to another destination, such as Mars or the Moon, the situation changes. The spacecraft is no longer in freefall around Earth, but is moving through interplanetary space. In that zone, Earth's gravitational influence weakens with distance according to Newton's law of gravity, where the force decreases with the square of the distance. Halfway to the Moon, about 192,000 km from Earth, Earth's gravity is barely 0.03% of what it is on the surface. On the journey to Mars, which can last between 6 and 9 months, astronauts spend most of the trip in an area where the gravitational influences of all nearby planets are so weak that the practical result is practically the same: microgravity.

The key difference between the two cases is that in orbit, microgravity is due to continuous freefall around a planet, while in interplanetary travel, it is due to the progressive distancing from any significant source of gravity. In both cases, the effect felt by the astronaut is very similar, but the physical origin is different.

What effects does microgravity have on the human body?

The human body has evolved over millions of years under the constant influence of Earth's gravity. All our systems, from the heart to the bones, are designed to function with that 9.8 m/s² pull acting on them. When that reference disappears, the organism responds with a cascade of changes that affect practically all its systems.

Respiratory level

In microgravity, the lungs continue to function normally in terms of gas exchange, but their internal distribution changes. On Earth, gravity causes the lower part of the lungs to receive more blood flow than the upper part. In space, this difference disappears and the distribution becomes more uniform, which theoretically improves respiratory efficiency. The mechanics of breathing itself do not require any special learning: the diaphragm and intercostal muscles work the same as on Earth, as their work depends on muscle contraction and not on gravity. What does change is that, without gravitational reference, astronauts do not feel their chest expanding downwards in the same way, which during the first few days can generate a slight sensation of shallow breathing until the body adapts.

As for air pressure, the ISS maintains an internal atmospheric pressure of approximately 101.3 kPa, practically identical to that at sea level on Earth. This is a deliberate engineering decision so that astronauts do not need any additional respiratory adaptation process and can work normally. The air composition is also similar to Earth's, with approximately 21% oxygen and 78% nitrogen. Some older capsules, such as those from the Apollo program, used pure oxygen atmospheres at lower pressure, which simplified the system but entailed a much higher risk of fire, as was tragically demonstrated in the Apollo 1 fire in 1967 that cost the lives of three astronauts.

Onboard oxygen production is one of the station's most critical systems. The ISS produces oxygen mainly through water electrolysis via the OGS (Oxygen Generation System), integrated into the Russian-made Elektron module and its American equivalent. This process separates water molecules into hydrogen and oxygen by applying electric current: oxygen is released into the cabin and hydrogen is used in the Sabatier system, which combines it with the CO2 exhaled by the astronauts themselves to produce water and methane. The recovered water returns to the OGS system to produce more oxygen, partially closing the cycle. Methane is expelled to the outside, representing a net loss from the system.

To produce the oxygen needed for a crew of 6 people, the system consumes approximately 2.5 kg of water per day. That is why the ISS also has the ECLSS (Environmental Control and Life Support System), which recycles practically all the water available on board: astronauts' urine, sweat, water vapor from the air, and condensed breath water. With all this, the station recovers approximately 90-93% of the water it consumes. As an additional backup, the station stores compressed oxygen cylinders and lithium perchlorate cartridges, which release oxygen by chemical reaction when heated and are used in emergency situations or when the main system fails.

However, that 7-10% of water that is not recovered, plus the expelled methane, means that the cycle is not completely closed and the station needs periodic external supplies. Resupply ships regularly carry additional water and consumable materials that the system uses. Without these resupply missions, oxygen production could not be maintained indefinitely. This is precisely one of the great challenges of a trip to Mars: during the 6-9 months of travel, there would be no possibility of resupply, so more efficient closed-cycle systems and oxygen production directly from the CO2 in the Martian atmosphere are being investigated, a technology that was already successfully tested by the MOXIE experiment aboard the Perseverance rover.

To compensate for elevated CO2 levels, the ISS has filtering systems that continuously monitor cabin gas levels. CO2 levels are maintained below 5.3 mmHg using lithium hydroxide scrubbers and catalytic CO2 reduction systems. Even so, typical levels on the station hover around 2-4 mmHg, significantly higher than the 0.3 mmHg in Earth's air, which contributes to the chronic fatigue and headaches that many astronauts report during long missions.

Cardiovascular level

This is one of the most affected systems. On Earth, the heart constantly works to pump blood upwards, against gravity. In microgravity, that effort disappears and bodily fluids shift towards the upper body and head. In the first few hours of exposure, the blood volume in the lower limbs can decrease by 10-15%, while the face swells and astronauts experience persistent nasal congestion similar to a cold. In response, the body reduces the total plasma volume by 10-22% in the first few days. The heart, needing less effort, progressively atrophies. After 6 months on the ISS, studies have documented a reduction in heart volume of up to 9%.

To mitigate these effects, astronauts perform mandatory daily cardiovascular exercise, combining sessions on a stationary bike and a treadmill with harnesses that hold them to simulate some load. Before returning to Earth, they follow a specific oral rehydration protocol, ingesting 1-2 liters of fluid with salts in the hours before landing to increase plasma volume and reduce the risk of orthostatic hypotension upon regaining gravity. In some cases, fludrocortisone, a mineralocorticoid that helps the body retain sodium and water, is administered, and pressure suits are worn on the legs during re-entry to prevent fainting.

Ocular and vision level

One of the most concerning findings of recent decades. The fluid shift to the head increases intracranial pressure, which puts pressure on the optic nerve and can flatten the eyeball. This syndrome is called VIIP (Visual Impairment and Intracranial Pressure) and affects more than 40% of astronauts on long missions. Its consequences include progressive hyperopia, choroidal folds, and damage to the optic nerve, which in some cases have been permanent. Scott Kelly, after his year on the ISS, reported a significant loss of visual acuity that took months to partially recover.

Currently, there is no completely effective treatment for VIIP, making it one of the biggest medical challenges for future Mars missions. Current measures include periodic eye monitoring during the mission using optic nerve ultrasound and optical coherence tomography. The use of negative pressure suits in the lower body, known as LBNP (Lower Body Negative Pressure), is being investigated to draw fluids to the legs and reduce intracranial pressure, with promising but not yet conclusive results. Astronauts also wear corrective glasses adapted to the vision changes they experience during the mission.

Cognitive and proprioception level

Proprioception is the body's ability to know where its parts are without needing to look at them. On Earth, the vestibular system in the inner ear, combined with muscle and joint receptors, gives us a constant reference of our position. In microgravity, this reference is completely distorted. During the first few days, between 60 and 80% of astronauts suffer from space adaptation syndrome, with nausea, vomiting, disorientation, and severe dizziness. At a cognitive level, neuroimaging studies conducted before and after long missions have shown structural changes in the brain, including a redistribution of cerebrospinal fluid and alterations in white matter that can affect processing speed, working memory, and fine motor coordination.

To manage space adaptation syndrome, NASA and other agencies administer promethazine or scopolamine during the first few days of the mission, anti-vertigo medications that reduce nausea and disorientation. Scopolamine is administered as a transdermal patch to facilitate its use in the microgravity environment. In addition, astronauts receive prior training in centrifuges and motion simulators to familiarize the vestibular system with disorientation situations. For long-term cognitive effects, there is not yet an established pharmacological protocol, although the role of aerobic exercise and cognitive stimulation during the mission as protective factors is actively being studied.

Auditory level

The auditory system itself is not directly damaged by microgravity, but it is indirectly affected. The increased intracranial pressure can cause a sensation of plugged ears and alterations in the perception of balance, as the inner ear manages both hearing and spatial orientation. Furthermore, the constant noise from the ISS ventilation systems and machinery, which continuously hovers around 65-70 decibels, represents an accumulated auditory stress factor over months that can contribute to slight high-frequency hearing loss.

To compensate, astronauts use hearing protection during noisier tasks, especially during physical exercises performed near machinery. NASA conducts periodic audiograms before, during, and after each mission to monitor the evolution of each astronaut's hearing. In addition, work is being done to improve the acoustic insulation of future space station habitable modules to reduce exposure to chronic noise, identified as one of the most underestimated health factors in life on board.

Musculoskeletal level

This is one of the most documented and serious effects. Without the need to support body weight, muscles atrophy quickly. Without active countermeasures, an astronaut can lose 20-30% of their muscle mass in just two weeks. Bones suffer a similar process: without mechanical load, osteoblasts reduce new bone formation and osteoclasts accelerate reabsorption, leading to a loss of bone density of 1-2% per month in load-bearing areas such as hips, femurs, and lumbar spine. For comparison, a person with severe osteoporosis loses approximately 1% per year.

To curb this deterioration, astronauts perform up to 2.5 hours of mandatory daily physical exercise combining three types of training: aerobic exercise on a stationary bike and treadmill with harnesses, and resistance exercise on the ARED (Advanced Resistive Exercise Device) machine, which simulates weights of up to 272 kg using vacuum cylinders. Diet also plays a key role, with a controlled intake of 1,000 to 1,200 mg of calcium daily and vitamin D, as the absence of natural sunlight compromises its synthesis. In some cases, the use of bisphosphonates, the same drugs used in the treatment of osteoporosis, is being studied to reduce bone reabsorption during long missions, although their routine use is not yet standardized. Despite all these measures, full recovery of bone density can take between 2 and 3 years after returning to Earth.

Gastrointestinal level

Microgravity also alters the digestive system. On Earth, digestion is aided by gravity, which helps the transit of gastric contents. In space, that support disappears, and the movement of food through the digestive system depends exclusively on peristalsis, the muscular movements of the intestine. This can lead to slowed gastric emptying, abdominal bloating, and constipation. At a microbiological level, studies from NASA's Twins Study, comparing Scott and Mark Kelly, showed significant changes in the composition of the gut microbiota during spaceflight, with a reduction in bacterial diversity that can affect immunity and digestion.

To compensate, astronauts' diets are carefully planned by specialized nutritionists to ensure sufficient fiber intake to promote intestinal transit. Fermented foods and probiotics are included to try to maintain microbiota diversity. In cases of severe constipation, mild laxatives can be used, although their use is minimized due to the practical difficulties of managing intestinal transit in a gravity-free environment. Furthermore, the chronic stress of the mission and the disruption of the circadian rhythm, with up to 16 sunrises daily on the ISS, also contribute to gastrointestinal deterioration, so managing rest and psychological well-being are also an indirect part of the digestive health protocol.

How is an astronaut's daily life in microgravity?

If the impact of microgravity on the body is already striking at a physiological level, it is even more so when it comes to everyday tasks. Things that on Earth we do completely automatically, without thinking, become procedures in space that must be learned, planned, and executed carefully.

Sleeping

In microgravity, there is no up or down, so an astronaut can technically sleep in any orientation and on any surface. In practice, ISS astronauts sleep in small individual compartments the size of a built-in closet, where they get into a sleeping bag secured to the wall to prevent them from floating away during the night. Sleeping untethered is possible, but the body tends to drift slowly and may end up bumping against a panel or pipe. Another significant problem is that without gravitational reference, the brain takes time to recognize the resting posture, and sleep quality is usually poorer. Added to this is the fact that on the ISS, the sun rises and sets every 90 minutes, completely disrupting the natural circadian rhythm. To compensate, the modules have artificial lighting that simulates Earth's light and dark cycles, and in some cases, melatonin or zolpidem is prescribed to help with sleep. Even so, astronauts report sleeping an average of 6 to 6.5 hours, below the recommended 8.

Eating

Food in space has evolved significantly since the purees in tubes of the early space programs. Today on the ISS, astronauts eat dehydrated, freeze-dried, or thermo-stabilized foods that are rehydrated with hot water directly in their packaging. Solid foods can be eaten normally as long as they don't crumble, as floating crumbs are a real danger: they can get into ventilation systems or astronauts' eyes and mouths. That's why bread is forbidden and replaced by tortillas. Utensils are normal, but trays and containers are attached to the table with Velcro or magnets so they don't fly around. Thick sauces and condiments are used without problems because surface tension keeps them attached to the food, but salt and pepper are only used in liquid dissolved form because in powder form they would disperse in the air.

Drinking

Drinking is one of the most visually striking tasks. In microgravity, liquids do not fall to the bottom of a glass but form floating spheres due to surface tension. That's why astronauts drink directly from sealed bags with straws, gently squeezing to propel the liquid. Opening a container with liquid in space without caution can cause the contents to shoot out in small floating droplets that adhere to surfaces or equipment. The water they consume largely comes from the ECLSS recycling system, which, as we already explained, recovers water vapor from the air, sweat, and treated urine. Coffee and tea are also consumed from sealed bags, and although it feels strange at first to drink without tilting the container, astronauts adapt in a few days.

Urinating and defecating

This is probably the most complex logistical challenge of daily life in space and one of the most surprising when the details are known. The ISS toilet works by air suction, just like a vacuum cleaner, to direct waste in the correct direction in the absence of gravity. To urinate, astronauts use a funnel connected to a suction hose, with anatomically adapted models for men and women. The urine is collected, filtered, and processed in the ECLSS system to convert it into drinking water, going through several purification phases that include centrifugal distillation, activated carbon filtration, and catalytic oxidation. To defecate, astronauts must position themselves precisely over an opening of barely 10 centimeters in diameter, for which they receive specific training with a simulator on Earth. Feces are stored in vacuum-sealed bags that are compacted and accumulated in uncrewed cargo ships that are incinerated upon re-entry into the atmosphere. All human waste management is meticulously protocolized because any leak in a closed space has immediate health consequences.

Hygiene

Conventional showering is impossible in microgravity because water doesn't fall but forms spheres that float and stick to any surface, including electrical panels. Astronauts clean themselves with wet wipes soaked in cleaning solution that doesn't require rinsing. For hair washing, they use no-rinse shampoos that are applied directly and wiped off with a towel. For brushing teeth, they use edible toothpaste that can be swallowed directly, thus avoiding the need to spit and rinse. Shaving is done with electric shavers equipped with integrated vacuums that collect cut hairs before they float away. Hygiene in space requires more time and planning than on Earth, and its care is essential to prevent infections in an environment where the immune system is already under stress.

Sneezing and coughing

Sneezing in space is a topic that causes more concern than it might seem. A sneeze projects saliva and mucus droplets at speeds of up to 160 km/h. On Earth, these droplets quickly fall to the ground due to gravity. In microgravity, they disperse in all directions and remain floating in the air for much longer, turning any respiratory illness into a difficult collective problem to contain in such a small, closed space. ISS health protocols include pre-launch quarantines to ensure that no astronaut boards the station with an active infection. Sneezing and coughing are managed by covering the mouth and nose with the elbow, just like on Earth, but the concern for particle dispersion is much greater.

Crying

Crying in space works completely differently from how it does on Earth. Tears are produced normally because the lacrimal gland does not depend on gravity to secrete fluid. But without gravity to make them fall down the cheek, tears accumulate in the eye, forming an increasingly large sphere of liquid that adheres to the eyeball due to surface tension. If the sphere grows too large, it eventually detaches and floats as a small ball of water. Astronaut Chris Hadfield described it firsthand during his stay on the ISS and published a viral video about it. Paradoxically, this makes crying in space more uncomfortable than on Earth because the liquid does not drain naturally and can cause eye irritation.

Mucous membranes

The nasal and respiratory tract mucous membranes are particularly affected in space. The fluid shift towards the head causes almost permanent nasal congestion during the first few days of the mission, similar to a chronic cold. The mucous membranes produce more mucus than usual in response to this increased pressure, which makes nasal breathing difficult and alters the sense of smell and taste. Many astronauts describe food tasting different in space, not only due to changes in mucous membranes but also because congestion reduces the ability to perceive aromas, which are fundamental to the gustatory experience. This congestion usually subsides partially two or three weeks into the mission, when the body adapts to the new fluid distribution, although it never completely disappears while remaining in microgravity.

Cleaning the spacecraft

Keeping the ISS clean is not a matter of comfort but of survival. In a closed space where six people live together for months without the possibility of venting to the outside, the accumulation of bacteria, fungi, and suspended particles can become a serious health problem. In fact, microbiological studies on the ISS have detected colonies of fungi and bacteria in ventilation ducts, rubber seals, and damp corners, some with the capacity to degrade technical materials of the station itself.

Cleaning is mainly done with damp disinfectant wipes, which astronauts use to clean surfaces, panels, handles, and equipment periodically following an established weekly routine. The filters of the ventilation systems are regularly replaced and cleaned because they are the main accumulators of particles, hair, dead skin, and microorganisms. Handheld vacuum cleaners are used to collect floating particles in the air and on surfaces, especially after meals or any activity that generates solid waste. Microbiological control is so important that NASA periodically cultures the air and surfaces of the station to monitor what microorganisms are present and in what concentrations, and has response protocols if potentially dangerous species are detected.

Washing clothes

There is no washing machine on the ISS. Washing clothes requires water, detergent, rinsing, and drying, and managing this entire process in microgravity with limited water resources is unfeasible with current technology. The solution is much simpler and more direct: clothes are not washed. Astronauts bring enough changes of clothes for the entire mission, calculated to change underwear every two or three days, and outer garments like shirts or pants approximately every week. When a garment is too worn, it is placed in a sealed bag and stored until it can be loaded onto an uncrewed supply ship which, upon re-entry into the atmosphere, is incinerated along with the rest of the station's solid waste.

Conventional footwear is also not used inside the station because the feet do not touch the ground. Astronauts wear thick socks and in some cases light booties for protection, as their feet are constantly used to anchor themselves to the bars and handles distributed throughout the station. This causes the soles of their feet to lose their usual toughness over weeks, while the tops of their feet, which rub against the handrails, progressively harden.

Sexuality

This is a topic that space agencies rarely discuss publicly. NASA does not have policies that prohibit sexual relations between astronauts, but it also does not regulate or facilitate them. In practice, the lack of privacy on the ISS and factors such as stress, chronic fatigue, and hormonal changes significantly reduce sexual desire during the mission.

Physically, the biggest challenge is that in microgravity, any applied force generates an opposite reaction, making it necessary to constantly hold on to maintain physical contact between two people. Solitary sexuality is also not prohibited, and agency psychologists recognize it as part of an astronaut's overall well-being, with individual rest compartments being the only space with some real privacy on the station.

Looking ahead to future missions to Mars, lasting between 18 months and 3 years, agencies are beginning to recognize that this is an aspect that will need to be addressed more openly in crew well-being protocols.

Infographic

🧑🚀

What happens to your body in space?

Microgravity transforms every system of the human body and turns the simplest tasks into engineering challenges.

Zero gravity does not exist. Astronauts experience microgravity: in orbit, centrifugal force equals gravity and everything appears to float. In interplanetary travel, the cause is the progressive distancing from any massive body.

🫀 Physiological effects of microgravity
Cardiovascular

Fluids shift to the head, the face swells, and persistent nasal congestion appears. Blood plasma decreases by 10% to 22% in the first few days. After 6 months, the heart can lose up to 9% of its volume.

Vision (VIIP syndrome)

Intracranial pressure flattens the optic nerve and deforms the eyeball. Affects more than 40% of astronauts on long missions. Can cause progressive hyperopia and permanent damage. It is one of the biggest medical obstacles for a trip to Mars.

Muscles and bones

Without mechanical load, up to 30% of muscle mass can be lost in 2 weeks. Bones lose between 1% and 2% of density per month, a rate up to 12 times higher than severe osteoporosis. Recovery can take 2 to 3 years.

2.5 h of mandatory daily exercise with stationary bike, treadmill with harnesses, and the ARED machine (simulates up to 272 kg of resistance)
Brain and proprioception

Between 60% and 80% of astronauts suffer intense nausea, vomiting, and disorientation in the first few days. Neuroimaging studies show structural changes in white matter that can affect working memory and fine motor coordination.

Respiratory

Lungs function normally, but blood flow distribution becomes uniform. The ISS produces oxygen through water electrolysis and recycles 90-93% of onboard water. CO₂ levels are up to 10 times higher than on Earth, contributing to chronic fatigue and headaches.

Digestive

Without gravity, transit depends only on peristalsis, causing bloating and constipation. Gut microbiota loses diversity, affecting immunity. The 16 daily sunrises on the ISS disrupt circadian rhythm and worsen the condition.

🛰️ Daily life in microgravity
🌍
On Earth

You sleep lying down, with gravitational reference

VS
🛸
In Space

You sleep tethered to the wall in a sleeping bag, averaging 6-6.5 hours

😢
Crying here

Tears fall down the cheek

VS
💧
Crying there

They accumulate in a sphere over the eye until they float

  • 🍞 Bread is forbidden. Crumbs float and can get into ventilation systems, eyes, and mouth. It is replaced by tortillas.
  • 🧂 Salt and pepper in liquid form. In powder form, they would disperse in the cabin air.
  • 🚿 No shower. Hygiene with wet wipes, no-rinse shampoo, and edible toothpaste.
  • 🚽 The toilet works by suction with an opening of only 10 cm. Astronauts train on Earth with a simulator. Urine is recycled into drinking water.
  • 👕 Clothes are not washed. Enough changes of clothes are brought for the entire mission. Used clothes are incinerated upon re-entry into the atmosphere along with the cargo ship.
  • 🤧 A sneeze is a collective problem. Droplets travel at 160 km/h and float indefinitely in the closed cabin.
  • 🦶 Feet transform. The sole loses its usual toughness from not stepping on the ground, while the upper part hardens from being used to grip bars.
📊 ISS in numbers
🌡️
101.3 kPa

Interior pressure identical to Earth's sea level

💨
27,600 km/h

Orbital velocity of the International Space Station

🌅
16 sunrises/day

A complete light and dark cycle every 90 minutes

♻️
90-93%

Of onboard water is recycled (urine, sweat, vapor, condensation)

FAQs. Frequently asked questions about life in microgravity in space

Why do astronauts float on the International Space Station if Earth's gravity is still acting on them?

Astronauts don't float because gravity has disappeared. At the ISS's altitude, about 408 kilometers, Earth's gravity retains approximately 90% of its intensity compared to the surface. What happens is that the station and everything inside it are in continuous freefall around Earth, moving at about 27,600 km/h. At that speed, the centrifugal force generated by orbital motion exactly balances the gravitational pull, so the resultant force on objects inside the spacecraft is practically zero. Everything falls at the same rate, which is why no one perceives the gravitational pull. The technical term for this situation is microgravity, not zero gravity.

What happens to an astronaut's heart during a long mission in space?

On Earth, the heart constantly works to pump blood upwards, against gravity. When this demand disappears in microgravity, bodily fluids redistribute towards the upper body and head, and the heart begins to atrophy as it no longer needs the same effort. In the first few days, blood plasma volume is reduced by 10% to 22%. After six months on the ISS, studies have documented a decrease in heart volume of up to 9%. To counteract this, astronauts perform mandatory daily cardiovascular exercise and follow rehydration protocols before returning to Earth, including the intake of fluids with salts and, in some cases, the use of drugs like fludrocortisone to prevent fainting upon regaining gravity.

How is oxygen produced inside the International Space Station?

The ISS produces oxygen primarily through water electrolysis, a process that separates water molecules into hydrogen and oxygen by applying electric current. Oxygen is released into the cabin, and hydrogen is utilized in the Sabatier system, which combines it with the CO2 exhaled by astronauts to generate water and methane. The recovered water returns to the electrolysis circuit, partially closing the cycle. Methane, however, is expelled to the outside, representing a net loss. To maintain this system, the station recycles approximately 90-93% of the water available on board, including urine, sweat, and breath vapor. Even so, this small unrecovered percentage necessitates periodic water supplies from Earth, making the complete closure of the cycle one of the major technological challenges for future missions to Mars.

Why can microgravity permanently damage astronauts' vision?

The fluid shift towards the head in microgravity causes a sustained increase in intracranial pressure. This pressure is transmitted to the optic nerve and can flatten the eyeball, altering its geometry and focusing ability. This condition is known as VIIP syndrome and affects more than 40% of astronauts on long missions. Its consequences include progressive hyperopia, choroidal folds, and damage to the optic nerve, which in some cases have been irreversible. Currently, there is no completely effective treatment, making this syndrome one of the biggest medical obstacles for crewed missions to Mars, where astronauts would spend between 18 months and 3 years exposed to microgravity without the possibility of early return.

How does the toilet work in space and what happens to the waste?

The ISS toilet works by air suction, similar to a vacuum cleaner, to direct waste in the correct direction without the help of gravity. To urinate, astronauts use a funnel connected to a suction hose, with designs adapted for men and women. Urine is collected and processed through distillation, activated carbon filtration, and catalytic oxidation until it becomes potable water. To defecate, they must position themselves precisely over an opening of barely 10 centimeters in diameter, a skill they practice beforehand in a simulator on Earth. Feces are stored in vacuum-sealed bags that accumulate until they are loaded onto uncrewed supply ships, which are incinerated upon re-entry into the atmosphere.

Why do astronauts lose muscle mass and bone density so quickly in space?

Without the need to support body weight against gravity, muscles lose their primary stimulus and atrophy at an alarming rate, potentially losing between 20% and 30% of their mass in just two weeks without countermeasures. In bones, the absence of mechanical load alters the balance between osteoblasts, which form new bone, and osteoclasts, which reabsorb it. The result is a loss of bone density of between 1% and 2% per month in load-bearing areas such as the hips and lumbar spine, a rate up to twelve times higher than that of severe osteoporosis. To counteract this, astronauts dedicate about 2.5 hours daily to mandatory exercise with devices like the ARED machine, and maintain a controlled intake of calcium and vitamin D. Even with all these measures, full recovery of bone density after return can take two to three years.

Why does food taste different in space?

The redistribution of fluids towards the head in microgravity causes almost permanent nasal congestion during the first few weeks of a mission, similar to a chronic cold. This congestion significantly reduces olfactory capacity, and since smell is responsible for much of the taste experience, astronauts perceive food with less intensity and nuance. Additionally, mucous membranes produce more mucus in response to increased pressure in the cranial area. Although congestion tends to partially subside after two or three weeks of adaptation, it never completely disappears while remaining in microgravity. This is why many astronauts prefer foods with intense flavors or resort to spicy sauces to compensate for this sensory loss.

What effects does cosmic radiation have on astronauts outside the protection of Earth's magnetosphere?

Although the ISS orbits within the magnetosphere, which offers some protection against radiation, astronauts receive significantly higher doses of radiation than they would on Earth's surface. On an interplanetary trip to Mars, outside Earth's magnetic shield, exposure to galactic cosmic rays and energetic solar particles would drastically increase. Studies with animal models and epidemiological data from astronauts have linked this prolonged exposure to an increased risk of cancer, cataracts, cardiovascular disease, and possible neurodegenerative effects. NASA estimates that a round trip to Mars would expose crew members to a cumulative dose close to the maximum allowed for their entire professional career, making radiation shielding one of the most critical technological challenges in deep space exploration.

Has the possibility of generating artificial gravity in spacecraft been investigated?

The idea of generating artificial gravity through rotation has been studied for decades as a possible solution to the health problems resulting from prolonged microgravity. The principle is simple: a structure rotating at a constant speed generates a centrifugal force that pushes occupants outward, simulating gravity. However, the engineering challenges are enormous. To produce a force equivalent to Earth's gravity with a rotation rate tolerable for the human vestibular system, the structure would need a radius of at least several hundred meters, which implies a cost and complexity of construction in space far beyond current capabilities. Agencies like NASA and ESA are investigating intermediate solutions, such as short-radius centrifuges that astronauts would use for limited periods per day, but none have yet been tested in actual long-duration missions.

How long does it take for the human body to readjust to Earth's gravity after a long space mission?

Readaptation to Earth's gravity is a gradual process that can extend for months or even years, depending on the physiological system affected. In the first hours after landing, many astronauts experience dizziness, orthostatic hypotension, and difficulty standing, as the cardiovascular system needs time to readjust fluid distribution and vascular tone. Motor coordination and balance usually normalize within the first few weeks, as the vestibular system recalibrates its references. Muscle mass can be recovered in about three to six months with intensive rehabilitation. However, bone density is the slowest parameter to restore: long-term follow-up studies have documented that some astronauts do not fully recover pre-mission bone density even three years after their return, especially in load-bearing areas such as the hip and femur.

References

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